Synthesis of breast cancer targeting conjugate of temporin-SHa analog and its effect on pro- and anti-apoptotic protein expression in MCF-7 cells
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چکیده
منابع مشابه
Synthesis Pyrano [2,3-c] Pyrazole-based compounds to induce apoptosis by reducing the expression of anti-apoptotic Bcl-2 protein in human breast cancer MCF-7 cells
Aim: Bcl-2 is a potential target for tumor treatment. The inhibition of the Bcl-2 production is research target of attract in the field of anti-cancer drug development. Recently, the assessment of antitumor activity appeared to be promising for pyrazole derivatives. Therefore, this study was designed to investigate the anti-cancer effects of novel pyrazole derivatives (HN1and HN2.). Material an...
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Background and Aim: Breast cancer is one of the most common types of cancer and the second leading cause of cancer death in women. The effect of ligustilide - isolated from the Kelussia on MCF-7 breast cancer cell line compared with human fibroblast cell line (HDF1BOM) was evaluated in the present study. Materials and Methods: MCF-7 and HDF1BOM cell lines were treated for 48 and 72 hours with ...
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Satureja khuzestanica Jamzad (Marzeh Khuzestani in Persian) is an endemic plant that iswidely distributed in the southern part of Iran. Despite the number of papers published on thisplant, no one has focused on its anticancer effects. Therefore, the present study was designedto investigate the selective cytotoxic and anti-proliferative properties of satureja khuzestanicatotal extract (SKE). MCF...
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Satureja khuzestanica Jamzad (Marzeh Khuzestani in Persian) is an endemic plant that iswidely distributed in the southern part of Iran. Despite the number of papers published on thisplant, no one has focused on its anticancer effects. Therefore, the present study was designedto investigate the selective cytotoxic and anti-proliferative properties of satureja khuzestanicatotal extract (SKE). MCF...
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هدف از آزمایش اول بررسی اثر سطوح مختلف سریسین [0 (control), 0.1, 0.5, 1.0, 2.5 %] افزوده شده به محیط , ivm بر cumulus cell expansion، بلوغ هسته و توسعه متوالی جنین، در گوسفندان نژاد سنجابی در فصل تولید مثلی می باشد. از سرگیری میوز به وسیله خارج شدن اولین پولار بادی اندازه گیری و هم چنین درصد رسیدن جنین های دو سلولی به مرحله کلیواژ و بلاستوسیت نیز به عنوان نشانه ای از میزان شایستگی توسعه اولیه ج...
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ژورنال
عنوان ژورنال: Peptides
سال: 2018
ISSN: 0196-9781
DOI: 10.1016/j.peptides.2018.07.002